Invasive Prenatal Diagnostics
What Are Chromosomal Abnormalities and When Do They Occur?
Chromosomal abnormalities often form during the earliest stages of fetal development. Thanks to modern diagnostic methods, many of these conditions — such as Down syndrome or Edwards syndrome — can be detected as early as the third month of pregnancy.
Invasive prenatal testing is recommended only in high-risk situations and is prescribed by an obstetrician-gynecologist when more precise confirmation of a potential genetic disorder is needed.
These procedures involve sampling biological material from inside the body, such as:
- Chorionic villi
- Placental tissue
- Amniotic fluid
- Fetal blood
While more accurate than non-invasive tests, these methods are more invasive and carry certain risks.
Who Should Consider Invasive Prenatal Diagnostics?
Your doctor may recommend this testing if:
- You are over 35 years of age
- Abnormalities were detected during first or second trimester screening
- Blood protein levels showed irregularities
- The pregnancy is a result of conception between close relatives
- A previous child had a genetic condition
- There is a family history of genetic diseases
- You have experienced previous miscarriages or stillbirths
- The pregnancy occurred after infertility treatment
- You were exposed to radiation or toxic chemicals
- There is an Rh incompatibility between you and the fetus
When Is It Not Recommended?
Because the procedure involves entering the uterus through the abdomen or cervix, it is not recommended in the following cases:
- Active infections or skin inflammation at the puncture site
- Poor blood clotting
- Pelvic adhesions
- Uterine abnormalities
- Signs of threatened miscarriage
Types of Invasive Prenatal Testing
Each method is chosen based on gestational age and clinical indications:
1. Chorionic Villus Sampling (CVS)
Performed between 10–13 weeks. A small sample of chorionic villi (embryonic placental tissue) is collected using a needle (through the abdomen) or a catheter (through the cervix). The villi share the fetus's genetic makeup.
2. Amniocentesis
Typically done at 15–16 weeks, and sometimes later in the second trimester (33–34 weeks). A small amount of amniotic fluid is taken through a thin needle inserted into the abdomen. This method detects chromosomal abnormalities, biochemical markers, and signs of oxygen deprivation.
3. Cordocentesis (Fetal Blood Sampling)
Done after 18 weeks, this test collects umbilical cord blood to analyze chromosomal structure, hormonal and biochemical levels, and possible infections. It is also used for in-utero blood transfusions in Rh incompatibility cases.
When Will Results Be Ready?
- Chorionic villus sampling: results typically within 2–4 days
- Amniocentesis: results may take over 2 weeks, due to the time needed to culture additional cells
- Cordocentesis: timelines vary depending on the analysis
Why Choose IPF for Invasive Prenatal Testing?
- Precise ultrasound guidance: Every procedure is performed by experienced doctors using real-time imaging for maximum accuracy and safety
- On-site laboratory: Faster results with cytogenetic testing (chromosome count), molecular-genetic testing(chromosomal structure), and biochemical testing (organ maturity, Rh compatibility risks)
- Comprehensive support: Our team ensures patient comfort, minimizes stress, and provides post-procedure care
- Personalized approach: We determine the most suitable diagnostic method based on your gestational age and risk group
To schedule a consultation and determine the most appropriate prenatal test for you,fill out the form on our website or call the contact numbers listed.We’re here to support you every step of the way.
Invasive Prenatal Diagnostics
Як проходить лікування?
How is the treatment going?
Записатись на прийом
Make an appointment
Application has been successfully sent